Facts about the bus from Brno to Prague. Compare all providers like FlixBus, RegioJet and Turancar that travel 58 times every day by bus from Brno to Prague in one click! Book your bus ticket from Brno to Prague starting from $8.91! Cheapest Bus. $8.91. The journey time between Brno and Modern Apartment Biskupska, Prague is around 2h 49m and covers a distance of around 254 km. Operated by Hungarian Railways (MƁV), Czech Railways (ČD), RegioJet and others, the Brno to Modern Apartment Biskupska, Prague service departs from Brno Hlavni Nadrazi and arrives in Modern Apartment Biskupska, Prague. Best stops along Brno to Prague drive. The top stops along the way from Brno to Prague (with short detours) are Sedlec Ossuary, Žižkov Television Tower, and St Barbara's Cathedral. Other popular stops include Telč, Brno Zoo, and The Konopiste Castle. Show only these on map. On average, the trip from Brno to Berlin takes around 9h 15m, although the fastest bus will take 7h 10m, on average. This is the time it takes to travel the 269 miles (434 km) that separate the two cities. FlixBus operates a bus from Brno to Prague once daily. Tickets cost 430 Kč - 600 Kč and the journey takes 2h 35m. Two other operators also service this route. Alternatively, RegioJet operates a train from Brno Main Train Station to Prague Central Train Station Wilsonova hourly. Tickets cost 250 Kč - 850 Kč and the journey takes 2h 42m. What companies run services between Brno, Czechia and Prague Airport (PRG), Czechia? RegioJet operates a train from Brno-Zidenice to Praha Hlavni Nadrazi every 3 hours. Tickets cost 250 Kč - 850 Kč and the journey takes 2h 23m. Alternatively, FlixBus operates a bus from Brno to Prague once daily. Brno to Copenhagen by train. The train journey time between Brno and Copenhagen is around 15h 19m and covers a distance of around 1399 km. This includes an average layover time of around 1h. Operated by Railways of Slovak Republic (ZSSK), Hungarian Railways (MƁV), Deutsche Bahn Eurocity and others, the Brno to Copenhagen train service departs What companies run services between Brno HlavnĆ­ NĆ”draÅ¾Ć­, Czechia and Prague, Czechia? RegioJet operates a train from Brno Main Train Station to Prague Central Train Station Wilsonova hourly. Tickets cost 250 Kč - 850 Kč and the journey takes 2h 42m. Railways of Slovak Republic (ZSSK) also services this route 6 times a week. The calculated flying distance from Brno to Prague is equal to 116 miles which is equal to 186 km. If you want to go by car, the driving distance between Brno and Prague is 208.44 km. If you ride your car with an average speed of 112 kilometers/hour (70 miles/h), travel time will be 01 hours 51 minutes. FlixBus operates a bus from Brno to Třebƭč once daily. Tickets cost 210 Kč - 290 Kč and the journey takes 1h. Alternatively, Czech Railways (ČD) operates a train from Brno Hlavni Nadrazi to Trebic hourly. Tickets cost 100 Kč - 220 Kč and the journey takes 1h 30m. Train operators. CBMXG.